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Autologous cells have longer manufacturing processes, higher costs, and limited redosing but exhibit stronger persistence and a lower risk for CRS. Allogeneic cells are a cheaper, more accessible patient treatment option but are less personalized and display shorter persistence, with a higher risk for CRS and GvHD.
CRS, cytokine release syndrome; GvHD, graft-versus-host disease; CAR-T, chimeric antigen receptor T
