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. Author manuscript; available in PMC: 2025 Sep 1.
Published in final edited form as: Am J Ophthalmol. 2024 May 2;265:224–235. doi: 10.1016/j.ajo.2024.04.014

FIGURE 2.

FIGURE 2.

Representative cases showing differing rates of sectoral retinal nerve fiber layer (RNFL) thinning between eyes with (A, B) and without (C, D) optic disc vessel density (ODVD) reduction. Serial whole-signal-mode en-face optical coherence tomography angiography (OCTA) images (A1, C1), serial maps of sectoral RNFL thickness (B1, D1), and scatterplots demonstrating the rate of ODVD change (A2, C2) and that of sectoral RNFL thinning (B2, D2). A and B, An eye with ODVD reduction had rapid deterioration of ODVD in the superior hemisphere (−8.09%/yr, P = 0.017; A1, A2) and rapid RNFL thinning of the compatible TS sector (−5.04 μm/yr, P = 0.019; B1, B2). C and D, An eye with stable ODVD in the inferior hemisphere (0.05%/yr, P = 0.989; C1, C2) had stable RNFL in the compatible TI sector (0.36 μm/yr, P = 0.270; D1, D2). Note that there was no notable change in the parapapillary deep-layer microvasculature in either eye.