Table 2.
Childhood-onset SLE distinct mRNA expression signature.
| Gene | mRNA expression of whole blood | ||
|---|---|---|---|
| HC | SLE | log2FC | |
| IFI44L | 393.843 | 4845.204 | 4.032 |
| RSAD2 | 217.026 | 2238.146 | 3.916 |
| IFI44 | 523.023 | 3676.303 | 2.93 |
| ISG15 | 986.898 | 6403.622 | 2.862 |
| IFIT3 | 335.800 | 2133.825 | 2.773 |
| IFIT1 | 141.922 | 938.985 | 2.763 |
| HERC5 | 736.220 | 4186.448 | 2.678 |
| EPSTI1 | 614.408 | 3373.188 | 2.626 |
| CMPK2 | 17.416 | 104.671 | 2.487 |
| LY6E | 970.134 | 5029.074 | 2.339 |
| USP18 | 18.634 | 112.943 | 2.311 |
| MX1 | 1880.578 | 8370.341 | 2.200 |
| PLSCR1 | 59.636 | 264.261 | 2.144 |
| DHX58 | 87.350 | 349.268 | 2.005 |
| IFIT5 | 74.106 | 282.966 | 1.897 |
| DDX60 | 126.238 | 486.555 | 1.857 |
| LGALS3BP | 44.160 | 164.974 | 1.776 |
| PRIC285 | 576.247 | 1803.682 | 1.668 |
| IFIH1 | 249.174 | 794.372 | 1.62 |
| PARP9 | 334.414 | 1045.296 | 1.612 |
| DDX58 | 87.434 | 259.063 | 1.566 |
| PARP12 | 302.447 | 920.821 | 1.494 |
| PARP14 | 486.234 | 1279.183 | 1.309 |
| IRF7 | 109.300 | 264.600 | 1.221 |
| IFITM1 | 3562.358 | 8238.550 | 1.154 |
| SP100 | 97.324 | 196.314 | 1.011 |
This table presents the gene expression profiles of these 26 hypomethylated, highly expressed genes in cSLE.