Table 2.

Clinical characteristics, diagnoses, outcomes of neonates with seizures.

Baby	Gestation (weeks)	Respiratory status at time of seizure		Seizure burden	Clinical seizure semiology	Laterality	Anti seizure medication used*	Muscle paralysis	Diagnosis(**)	MRI finding (***)	Outcome and neurological exam at discharge
		ventilated	FiO2
1	38	Yes	100%	High	No clinical seizures	Right	Ph,Md	no	HIE	Acute ischemic change within the cortex of both cerebral hemispheres	Alive, normal
2	38	Yes	100%	High	Left arm twitching	Bilateral	Ph, Py, Md	yes	HIE	Not done	Died
3	40	Yes	21%	High	Left arm and leg clonic jerking	Bilateral	Ph, Py, Md	no	Perinatal Stroke	Bilateral ischemic changes of the left MCA territory with ischemic change within the left PLIC	Alive, central hypotonia with significant head lag
4	41	Yes	21%	Low	Rhythmic jerking of all four limbs	Bilateral	Ph	no	HIE	Normal	Alive, normal
5	38	Yes	100%	High	Extensor posturing of right arm and cycling movements	Bilateral	Ph	no	HIE	Severe hypoxic ischemic injury of bilateral basal ganglia, thalami and PLIC	Alive, tube feeds
6	39	Yes	21%	High	Left arm twitching with desaturations	Right	Ph	no	HIE	Normal	Alive, normal
7	36	Yes	21%	Low	Clonic jerks in arms	Bilateral	Ph, Md	no	HIE	Severe hypoxic ischemic injury of bilateral basal ganglia, thalami, PLIC, optic tracts	Alive, central hypotonia with significant head lag
8	40	No	21%	High	Left sided arm and leg → generalisation	Bilateral	Ph,Py,Md	no	IVH	Moderate volume intraventricular hemorrhage with early hydrocephalus	Alive, normal
9	41	Yes	100%	High	Tonic jerks left upper limb	Right	Ph. Md	yes	Perinatal Stroke	Encephalomalacia - distribution suggestive of right MCA infarction	Alive, tone abnormalities at discharge
10	37	Yes	100%	High	All four limbs - rhythmic jerking	Bilateral	Ph,Py,Md,Lt	yes	ARPKD	Severe global ischemic changes	Died
11	38	Yes	30%	High	All four limbs - rhythmic twitching and abnormal posturing	Bilateral	Ph, Md, Py	no	HIE, hypoglycemic	Severe white matter changes bilaterally	Alive, abnormal tone and movements at discharge and needed NG feeds

*Ph Phenobarbitone, Py Phenytoin, Md Midazolam, Lt Levetiracetam; Diagnosis column abbreviations (**): HIE hypoxic ischaemic encephalopathy, ARPKD autosomal recessive polycystic kidney disease. MRI column abbreviations (***): MCA middle cerebral artery, PLIC posterior limb of the internal capsule. Outcome abbreviation: NG naso-gastric.