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. 2024 Jul 10;111(8):1700–1716. doi: 10.1016/j.ajhg.2024.06.007

Table 1.

Tajima’s D statistic for MUC5B in the 1KG

GRCh38 chromosome 11 bin
Population Gene 1,220,000 1,230,000 1,240,000a 1,250,000a 1,260,000 1,270,000
AFR MUC5B Tajima’s D −1.09 −1.47 −1.84c,d −1.87c,d −1.94c,d −2.10c,d
# SNPs 180 162 444 279 209 248
EUR MUC5B Tajima’s D −0.44 −0.42 −1.49 −1.39 −1.56 −1.60
# SNPs 122 81 356 191 73 103
SAS MUC5B Tajima’s D −0.55 −0.96 −1.76b −1.77b −1.59 −1.65
# SNPs 140 100 328 188 85 102
EAS MUC5B Tajima’s D −0.25 −0.49 −1.58 −1.69b −2.13c,d −1.91b
# SNPs 109 62 189 109 79 83
AMR MUC5B Tajima’s D −0.46 −1.22 −1.84 −1.87b −1.95b −1.90b
# SNPs 130 110 353 201 108 122

Bin sizes of 10 kbp were used to compare values to the autosome-wide distribution per population in the 1KG cohort.19

a

Corresponds to bin containing VNTR sequence.

b

Bottom 10% of autosome-wide Tajima’s D values.

c

Bottom 5% of autosome-wide Tajima’s D values.

d

Significant at α = 0.05 after permutation testing.