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. 2024 Jul 10;111(8):1700–1716. doi: 10.1016/j.ajhg.2024.06.007

Table 2.

Tajima’s D statistic for MUC5AC in the 1KG

GRCh38 chromosome 11 bin
Population Gene 1,150,000 1,160,000 1,170,000 1,180,000a 1,190,000a 1,200,000 1,210,000
AFR MUC5AC Tajima’s D −1.06 −1.57 −1.37 −1.25 −0.98 −0.57 −1.23
# SNPs 213 268 428 259 241 226 166
EUR MUC5AC Tajima’s D −0.48 −1.37 −0.85 −0.54 0.17 0.52 −0.66
# SNPs 116 193 304 186 148 110 82
SAS MUC5AC Tajima’s D −0.70 −1.52 −1.63 −1.46 −0.71 −0.28 −0.87
# SNPs 134 191 312 194 154 132 92
EAS MUC5AC Tajima’s D −0.62 −1.74b −2.04c,d −1.70b −0.94 −0.31 −1.28
# SNPs 105 173 292 152 127 100 85
AMR MUC5AC Tajima’s D −0.79 −1.54 −1.39 −1.26 −0.93 −0.90 −1.29
# SNPs 140 196 300 192 183 170 109

Bin sizes of 10 kbp were used to compare values to the autosome-wide distribution per population in the 1KG cohort.19

a

Corresponds to bin containing VNTR sequence.

b

Bottom 10% of autosome-wide Tajima’s D values.

c

Bottom 5% of autosome-wide Tajima’s D values.

d

Significant at α = 0.05 after permutation testing.