Table 2.
GRCh38 chromosome 11 bin | |||||||||
---|---|---|---|---|---|---|---|---|---|
Population | Gene | – | 1,150,000 | 1,160,000 | 1,170,000 | 1,180,000a | 1,190,000a | 1,200,000 | 1,210,000 |
AFR | MUC5AC | Tajima’s D | −1.06 | −1.57 | −1.37 | −1.25 | −0.98 | −0.57 | −1.23 |
# SNPs | 213 | 268 | 428 | 259 | 241 | 226 | 166 | ||
EUR | MUC5AC | Tajima’s D | −0.48 | −1.37 | −0.85 | −0.54 | 0.17 | 0.52 | −0.66 |
# SNPs | 116 | 193 | 304 | 186 | 148 | 110 | 82 | ||
SAS | MUC5AC | Tajima’s D | −0.70 | −1.52 | −1.63 | −1.46 | −0.71 | −0.28 | −0.87 |
# SNPs | 134 | 191 | 312 | 194 | 154 | 132 | 92 | ||
EAS | MUC5AC | Tajima’s D | −0.62 | −1.74b | −2.04c,d | −1.70b | −0.94 | −0.31 | −1.28 |
# SNPs | 105 | 173 | 292 | 152 | 127 | 100 | 85 | ||
AMR | MUC5AC | Tajima’s D | −0.79 | −1.54 | −1.39 | −1.26 | −0.93 | −0.90 | −1.29 |
# SNPs | 140 | 196 | 300 | 192 | 183 | 170 | 109 |
Bin sizes of 10 kbp were used to compare values to the autosome-wide distribution per population in the 1KG cohort.19
Corresponds to bin containing VNTR sequence.
Bottom 10% of autosome-wide Tajima’s D values.
Bottom 5% of autosome-wide Tajima’s D values.
Significant at α = 0.05 after permutation testing.