Table 3.

Multivariate analysis of prognostic factors for overall and event-free survival in 529 pediatric AML patients

Variables	Overall survival(OS)		Event-free survival(EFS)
	HR(95%CI)	P value	HR(95% CI)	P value
NUP98::NSD1 (+)/FLT3/ITD(+)	1.3(0.5,3.2)	0.618	3.2(1.6,6.5)	0.001
NUP98::NSD1 (-)/FLT3/ITD(+)	1.1(0.5,2.5)	0.824	1.5(0.8,2.9)	0.170
NUP98::NSD1 (+)/FLT3/ITD(-)	0.8(0.2,2.4)	0.641	1.0(0.4,2.5)	0.971
Age > 10years	1.1(0.8,1.6)	0.420	0.9(0.7,1.2)	0.662
high risk group	1.2(0.5,2.7)	0.712	0.9(0.5,1.8)	0.840
NMP1 mutation	1.0(0.3,3.2)	0.990	1.0(0.4,2.7)	0.991
WT1 mutation	1.8(1.0,3.2)	0.040	1.7(1.1,2.8)	0.020
WBC > = 100 × 10^9/L	1.5(1.1,2.2)	0.013	1.6(1.2,2.1)	0.001