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IC50 for IL-1β Release, Mammalian Cell Viability, and C. albicans MIC50 Values for Compound 10, analogs 10a, 10c, 10g, and the Herbicidal Sulfonylurea Chlorimuron Ethyl (Compound 13)
| Compound | IC50(μM) ± SD | %viability ± SD | MIC50 (μM) ± SD |
|---|---|---|---|
| 10 | 2.3 ± 0.8 | 101.5 ± 1.4 | 6.4 ± 2.6 |
| 10a | 5.9 ± 0.5 | 106.5 ± 4.5 | 5.3 ± 1.1 |
| 10c | 2.9 ± 0.2 | 102.6 ± 6.0 | 27.3 ± 4.3 |
| 10g | 12.4 ± 1.7 | 99.0 ± 6.2 | >50 |
| 13 | >50 | 103.2 ± 7.3 | 0.5 ± 0.2 |
