Table 2.
Disease-specific survival of colorectal cancer patients.
| Characteristics | Total (N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
| Gender | 621 | ||||
| Female | 290 | Reference | |||
| Male | 331 | 1.207 (0.769–1.895) | 0.412 | ||
| Age | 621 | ||||
| ≤65 yrs | 273 | Reference | |||
| >65 yrs | 348 | 1.421 (0.894–2.257) | 0.137 | ||
| Histological type | 612 | ||||
| Adenocarcinoma | 533 | Reference | |||
| Mucinous adenocarcinoma | 79 | 1.195 (0.631–2.262) | 0.585 | ||
| CEA level | 413 | ||||
| ≤5 ng/mL | 259 | Reference | Reference | ||
| >5 ng/mL | 154 | 2.812 (1.566–5.050) | <0.001 | 1.393 (0.691–2.810) | 0.354 |
| Anatomic neoplasm subdivision | 594 | ||||
| Colon | 487 | Reference | |||
| Rectum | 107 | 0.912 (0.481–1.732) | 0.779 | ||
| Pathologic stage | 601 | ||||
| Stage I | 111 | Reference | Reference | ||
| Stage II | 228 | 2.741 (0.618–12.165) | 0.185 | 69587464.4550 (0.000-Inf) | 0.997 |
| Stage III | 174 | 6.688 (1.571–28.477) | 0.010 | 98248212.7528 (0.000-Inf) | 0.997 |
| Stage IV | 88 | 27.388 (6.598–113.686) | <0.001 | 325344207.7492 (0.000-Inf) | 0.997 |
| Residual tumor | 508 | ||||
| R0 | 466 | Reference | Reference | ||
| R1-R2 | 42 | 6.452 (3.789–10.987) | <0.001 | 2.023 (0.904–4.525) | 0.086 |
| MARCHF9 | 621 | ||||
| Low | 310 | Reference | Reference | ||
| High | 311 | 2.077 (1.302–3.312) | 0.002 | 2.510 (1.171–5.382) | 0.018 |