Table 3.
Clinical decision limits for XN-HPC
| Poor | Less-than-optimal | Good | P-value | |
|---|---|---|---|---|
| CD34 + × 106 cells/kg | < 2 | 2 to < 5 | ≥ 5 | |
| No. of donors | 41 | 133 | 120 | |
| Age, Mean ± SD | 43 ± 17 | 32 ± 14 | 30 ± 12 | 0.1350 |
| Male, (%) | 51% | 70% | 83% | < 0.0001 |
| BMI, Mean ± SD | 22.96 ± 4.25 | 23.58 ± 4.31 | 25.16 ± 4.14 | 0.0035 |
| XN-HPC × 106/L, Median (IQR) | 960.00 (695.25–1510.00) | 1670.00 (1259.75–2435.00) | 2715.50 (2002.50–3505.50) | < 0.0001 |
| AUC | 0.788 | 0.800 | ||
| Optimal Cut-off (Sensitivity, Specificity) | – | 1029 (89.47, 60.98) | 2154 (76.44,72.50) | |
| Diagnostic Cut-off (Sensitivity, Specificity) | – | 3974 (3.73, 100.00) | 5318 (3.31,100.00) |
BMI, body mass index; AUC, area under the receiver operating characteristic curve