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. 2024 Aug 24;14:19678. doi: 10.1038/s41598-024-69144-6

Table 2.

MIC and MLC results illustrating the minimum inhibitory concentration for the control (vancomycin unprocessed by iDPC), processed vancomycin, iDPC 10%—a 10:90 L-glutamic acid: vancomycin formulation, iDPC 45%—a 45:55 L-glutamic acid: vancomycin formulation, iDPC 80%—a 45:55 L-glutamic acid: vancomycin formulation. The process parameters of the iDPC formulations are as follows: 2.5 min of pre-processing time, 17.5 min of process time, 22.5 l/min flow rate, 95 relative centrifugal force (RCF).

Formulation MIC (μg/mL) MLC (μg/mL)
Control 3.125 6.25
Processed vancomycin 3.125 6.25
iDPC 10% 3.125 6.25
iDPC 45% 3.125 6.25
iDPC 80% 3.125 6.25