Table 2.
MIC and MLC results illustrating the minimum inhibitory concentration for the control (vancomycin unprocessed by iDPC), processed vancomycin, iDPC 10%—a 10:90 L-glutamic acid: vancomycin formulation, iDPC 45%—a 45:55 L-glutamic acid: vancomycin formulation, iDPC 80%—a 45:55 L-glutamic acid: vancomycin formulation. The process parameters of the iDPC formulations are as follows: 2.5 min of pre-processing time, 17.5 min of process time, 22.5 l/min flow rate, 95 relative centrifugal force (RCF).
| Formulation | MIC (μg/mL) | MLC (μg/mL) |
|---|---|---|
| Control | 3.125 | 6.25 |
| Processed vancomycin | 3.125 | 6.25 |
| iDPC 10% | 3.125 | 6.25 |
| iDPC 45% | 3.125 | 6.25 |
| iDPC 80% | 3.125 | 6.25 |