Table 1.

Synthesis details for VLCFAs. NMR data for numbered compounds are available in SI.

Alkyne	Bromoalkanoic acid	VLCFA	Yield (%)
1-octyne	12-bromododecanoic acid	(13Z)-eicosenoic acid (1)	˃ 95
1-octyne	14-bromotetrdecanoic acid	(15Z)-docosenoic acid (2)	86
1-octyne	16-bromohexadecanoic acid	(17Z)-tetracosenoic acid (3)	80
1-octyne	18-bromooctadecanoic acid	(19Z)-hexacosenoic acid (4)	78
1-octyne	20-bromoeicosenoic acid	(21Z)-octacosenoic acid (5)	65
1-decyne	16-bromohexadecanoic acid	(17Z)-hexacosenoic acid (6)	71
1-decyne	18-bromooctadecenoic acid	(19Z)-octacosenoic acid (7)	90
1-tridecyne	9-bromononanoic acid	(10Z)-docosenoic acid (8)	77
1-tridecyne	11-bromoundecanoic acid	(12Z)-tetracosenoic acid (9)	44
1-tridecyne	13-bromotridecanoic acid	(14Z)-hexacosenoic acid (10)	53
1-tridecyne	15-bromopentadecanoic acid	(16Z)-octacosenoic acid (11)	50