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. 2024 Aug 24;38:03946320241276336. doi: 10.1177/03946320241276336

Figure 7.

Figure 7.

RDH10 regulates PI3K-AKT pathway in SCG cells. (A) DEGs between high-RDH10 and low-RDH10 groups in TCGA. (B) DEGs for GO enrichment analysis. (C) DEGs for KEGG enrichment analysis. (D-E) Heatmap showed the relation between RDH10 level and multiple cancer-related pathways. (F) RDH10 was positively corelated with scores of PI3K-AKT pathway. (G) PI3K-AKT pathway was inhibited after RDH10 knockdown and enhanced after RDH10 overexpression in SCG1 cells. (H) PI3K-AKT pathway was inhibited after RDH10 knockdown and enhanced after RDH10 overexpression in SCG2 cells. *p < .05; **p < .01; ***p < .001.