Table 2.

Associations Between Cognitive Function and Glucose Variability

Cognitive function variables	Mean glucose	Time in range	MODD	MAGE	<70 mg/dL	>180 mg/dL	CV	SD
PROMIS total score	0.20	0.53**	0.13	0.21	0.17	0.18	–0.62*	0.13
Trails A	0.04	0.61**	0.01	0.04	0.17	–0.035**	0.21	0.06
Trails B	0.05	0.68**	0.00	0.23	0.03	0.05	0.11	0.09
Stroop test	0.04	0.50**	0.10	0.03	–0.74**	0.03	0.08	0.02
Digit-Symbol Substitution	0.18	0.16	0.23	0.06	0.03	0.17	0.05	0.16
Immediate recognition	0.05	0.01	0.07	0.15	0.09	0.02	0.17	0.14
Delayed recognition	0.05	0.13	0.18	0.28	0.04	0.01	0.03	0.09

Abbreviations: CV, coefficient of variation; MAGE, mean amplitude of glucose excursions; MODD, mean of daily differences; SD, standard deviation.

^*P < 0.05. **P < 0.01.