Table 2.
Comparison of metabolic decompensation at diagnosis of T1D between probands and first-degree relatives who developed T1D during follow-up.
| Probands n=22 | First-degree relativesn=23 | p-value | |
|---|---|---|---|
| Age at diagnosis (years) | 8.5 (5.2-11.4) | 16.1 (9.9-26.5) | 0.003c |
| Sex (male) | 11/22 (50.0) | 10/23 (43.5) | 0.661a |
| Glucose (mmol/L) | 18.6 (13.3-29.9) | 16.4 (12.2-21.7) | 0.154c |
| HbA1c (%) | 10.0 (8.2-11.3) | 7.4 (6.7-9.0) | 0.001c |
| Presence of DKA | 9/22 (40.9) | 1/23 (4.3) | 0.004b |
| Hospital stay (days) | 8.5 (6.7-11.0) | 0.0 (0.0-4.0) | < 0.001c |
| ICU admission (days) | 5/22 (22.7) | 0/23 (0.0) | 0.022b |
Sex, DKA, and ICU admission are shown as n/total (%). Rest of variables are shown as median (IQR: P25–P75). DKA, diabetic ketoacidosis. ICU, intensive care unit. HbA1c, glycated hemoglobin A1c. aPearson’s chi-square test. bFisher exact test. c Mann–Whitney U-test.