FIGURE 1.

Hemodynamics relationships associated with ICP In the first relationship (1.), ABP acts as the system inflow pressure with ICP opposing outflow pressure when it exceeds central venous pressure (CVP). In the second (2.), the ABP-ICP difference defines the background pressure gradient (CPP). The third (3.) is the pressure-flow relationship: CBF is determined by the pressure gradient subject under vasoregulation and other influences. The relationship (4.) identifies the co-dependence of functioning CA and CBF (or available oxygen/nutrients beyond the scope of this discussion).