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. 2024 Aug 25;44(1):355. doi: 10.1007/s10792-024-03283-7

Table 1.

Comparative findings in various types of additive keratoplasty for keratoconus

Author Year Country Study design Number of eyes Mean age Type of treatment Pocket depth Form of the lenticule Follow-up (months) Findings
Jafarinasab et al. [22] 2021 India Prospective 5 29 Femtosecond Laser-assisted Allogenic Stromal Keratoplasty With or Without Excimer Laser Donor Keratomileusis 360 µm concave 28.4 A regularization of the anterior surface of the cornea was achieved, along with a correction of refractive errors
Pedrotti et al. [28] 2021 Italy Trial 34 / Femtosecond laser-assisted stromal lenticule addition 200 µm above the endothelium biconvex / The corneal thickness was improved, and there was a satisfactory restoration of the posterior surface
Pedrotti et al. [54] 2023 Italy Prospective 15 47 Femtosecond intrastromal lenticular implantation 100 µm above the endothelium positive meniscus lamella 12 MS-SLAK appears to be effective in achieving corneal surface regularization
Ganesh et al. [24] 2015 India Prospective 6 19.5 FILI accelerated collagen cross-linking 100 µm donut-shape 6 A clinical improvement in best corrected visual acuity was observed, along with a flattening of mean keratometry in both the 3-mm and 5-mm zones, accompanied by a reduction in higher-order aberrations
Mastropasqua et al. [23] 2018 Italy / 10 / Stromal lenticule addition keratoplasty / negative meniscus lamella 6 The negative meniscus-shaped lenticule addition induced corneal flattening, resulting in an improvement in visual acuity
Jadidi et al. [52] 2018 Iran Prospective 4 27.25 FAISCG 250 µm central keratoconus- circular shape; inferior keratoconus- crescent shape; in asymmetric bow-tie keratoconus- round shape 12 They successfully achieved a reduction in Kmax, accompanied by improvements in both best corrected visual acuity and spherical equivalent
Jin et al. [26] 2019 China Retrospective 11 22.18 Small-incision femtosecond laser–assisted intracorneal concave lenticule implantation 160 µm concave 24 The SFII group demonstrated enhanced corneal regularization, leading to superior visual acuity outcomes within the same group
Doroodgar et al. [53] 2020 Iran Prospective 22 / Femtosecond laser with customized Stromal Lenticule Implantation / simple necklace or necklace-with-ring shape / An improvement was achieved in vision, topography, and refraction

MS-SLAK, meniscus-shaped stromal lenticule addition keratoplasty; FILI, femtosecond intrastromal lenticular implantation; FAISCG, femtosecond-assisted intrastromal corneal graft; Kmax, maximum curvature power; SFII, small-incision femtosecond laser-assisted intracorneal concave lenticule implantation