Table 2.
Logistic regression analysis for marasmus type malnutrition (n = 243/2,308 patients).
| Univariable | Multivariable | |||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Age | 1.004 (0.995–1.014) | 0.343 | 1.006 (0.992–1.019) | 0.423 |
| Male sex | 0.530 (0.405–0.692) | < 0.001 | 0.779 (0.539–1.125) | 0.182 |
| Systolic blood pressure | 0.992 (0.987–0.997) | 0.001 | 0.990 (0.983–0.998) | 0.013 |
| Heart rate | 1.003 (0.998–1.008) | 0.238 | NS | |
| NYHA class 3 or 4 | 1.783 (1.093–2.907) | 0.020 | 1.064 (0.543–2.085) | 0.857 |
| Atrial fibrillation | 0.989 (0.753–1.300) | 0.939 | NS | |
| Coronary artery disease | 0.550 (0.398–0.761) | < 0.001 | 0.802 (0.493–1.305) | 0.374 |
| Stroke | 1.073 (0.766–1.504) | 0.682 | NS | |
| COPD | 1.014 (0.735–1.398) | 0.933 | NS | |
| Malignant tumor | 1.593 (1.164–2.179) | 0.004 | 1.438 (0.938–2.204) | 0.096 |
| RASIs | 0.564 (0.429–0.740) | < 0.001 | 0.555 (0.386–0.799) | 0.002 |
| Beta blockers | 0.983 (0.732–1.320) | 0.907 | NS | |
| MRAs | 1.355 (1.037–1.770) | 0.026 | 1.017 (0.676–1.530) | 0.935 |
| Loop diuretics | 1.629 (1.201–2.211) | 0.002 | 1.321 (0.830–2.104) | 0.241 |
| Statins | 0.475 (0.350–0.645) | < 0.001 | 0.645 (0.419–0.993) | 0.047 |
| Antihyperuricemic agents | 0.724 (0.512–1.022) | 0.066 | NS | |
| ICD or CRT | 0.980 (0.668–1.437) | 0.917 | NS | |
| Log-BNP | 2.051 (1.565–2.687) | < 0.001 | 1.648 (1.152–2.358) | 0.006 |
| Hemoglobin | 0.820 (0.772–0.871) | < 0.001 | 0.871 (0.796–0.953) | 0.003 |
| Lymphocytes | 0.982 (0.967–0.997) | 0.019 | 0.998 (0.979–1.018) | 0.873 |
| eGFR | 1.007 (1.001–1.012) | 0.023 | 1.010 (1.002–1.019) | 0.014 |
| Sodium | 0.920 (0.889–0.951) | < 0.001 | 0.931 (0.890–0.974) | 0.002 |
| Uric acid | 0.916 (0.848–0.989) | 0.025 | 0.977 (0.885–1.079) | 0.647 |
| C-reactive protein | 1.021 (0.985–1.060) | 0.225 | NS | |
| Total cholesterol | 1.000 (0.995–1.004) | 0.859 | NS | |
| HbA1c | 0.710 (0.595–0.847) | < 0.001 | 0.724 (0.564–0.930) | 0.011 |
| LVEF | 1.000 (0.989–1.010) | 0.933 | NS | |
Age, male sex, and variables with P values of < 0.05 were entered into multivariable model.
OR, odds ratio; CI, confidence interval; NYHA, New York Heart Association; COPD, chronic obstructive pulmonary disease; RASI, renin-angiotensin system inhibitor; MRA, mineralocorticoid receptor antagonist; ICD, implantable cardioverter-defibrillator; CRT, cardiac resynchronization therapy; Log-BNP, log-transformed B-type natriuretic peptide; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin; LVEF, left ventricular ejection fraction; NS, not selected.
Age, systolic blood pressure, heart rate, log-BNP, hemoglobin, lymphocytes, eGFR, sodium, uric acid, C-reactive protein, total cholesterol, HbA1c, and LVEF were analyzed as continuous variables.