RpalOR1 and RferOR1 are activated by host plant volatiles. (A) Action potential frequency of Drosophila at1 OSNs expressing RpalOR1 or RferOR1 in response to palm tree volatiles and structurally related molecules (100 µg in the stimulus cartridge). Dark blue and orange colours show significant differences from the solvent (Kruskal-Wallis test followed by a Dunnett's multiple comparison test with a Benjamini & Hochberg correction, n = 12–38, *p < 0.05, ⁎⁎p < 0.01, ⁎⁎⁎p < 0.001). (B) Dose-response experiments performed on at1 OSNs expressing RpalOR1 or RferOR1 with the three best agonists. Box plots show the median and the first and third quartiles of the distribution, whiskers show data distribution below the first quartile and above the third quartile, and dots show outliers. No significant difference was observed between RpalOR1 and RferOR1 responses to a given odorant dose (Kruskal-Wallis test followed by a Dunn's multiple comparison test with a Benjamini & Hochberg correction, n = 13–16, p > 0.05).