Table 1.

Changes in Diarrhea-Related Mortality Among Children <5 Years of Age in the Postvaccine Period Compared With the Prevaccine Period, by Age Group

	Median Annual No. of Diarrhea-Related Deaths		Median Annual Diarrhea-Related Death Rate (No. of Deaths per 100 000 Under-5 Children)		Absolute Reduction		Relative Reduction in Death Rate, % (95% CI)	P Value
Age Group	Prevaccine	Postvaccine	Prevaccine	Postvaccine	No. of Deaths	Death Rate (No. of Deaths per 100 000 Under-5 Children)
All ages (0–59 mo)	1794	835	15.8	7.5	959	8.3	53 (47–58)	<.001
≤11 mo	1198	563	52.7	25.4	635	27.3	52 (45–59)	<.001
12–23 mo	421	158	18.6	7.1	264	11.5	62 (50–73)	<.001
24–59 mo	175	114	2.6	1.7	61	0.9	34 (15–53)	<.001
Congenital heart defect 0–59 mo	3177	3362	27.9	30.1	−186	−2.2	−8 (−13 to −3)	<.001

P values were calculated with the use of a χ² test. Negative values imply relative increase. Prevaccine period was defined as January 2003 to December 2006. Postvaccine period: age ≤11 months from January 2008 to December 2014, age 12–23 months from January 2009 to December 2014, and age 24–59 months from January 2010 to December 2014.

Abbreviation: CI, confidence interval.