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. Author manuscript; available in PMC: 2024 Aug 26.
Published in final edited form as: Nat Immunol. 2022 Jul 6;23(7):1021–1030. doi: 10.1038/s41590-022-01255-6

Extended Data Fig. 8 |. Gsdmd deficiency does not interfere with IL-33/St2 downstream events in mice.

Extended Data Fig. 8 |

a, Flow cytometry analyzed cell numbers of lung total from wide-type and Gsdmd−/− mice treated with recombinant murine IL-33 (or PBS for the control group) for continuous 4 days. b, Flow cytometry analyzed SiglecF+CD11c− eosinophils from BAL fluids as in a. c, Flow cytometry analyzed SiglecF-CD11c−CD11b+ neutrophils from BAL fluids as in a. d, Flow cytometry analyzed SiglecF+CD11c+ macrophages from BAL fluids as in a. e, Flow cytometry analysis of Lin−CD90.2+ST2+ ILC2 from mice lungs as in a. Flow cytometry analyzed cell numbers of IL-5+ ILC2 (f), IL-13+ ILC2 (g) and IL-5+ IL-13+ ILC2 (h) in mice lungs as in a. Results are depicted as means ± SEM, n = 5 using the two-tailed, Mann–Whitney test, and Dunnett’s multiple comparisons test. Data are representative of two independent experiments with similar results.