Table 2. Characteristics of the Capsule PK Profiles and Corresponding In Vitro Dissolution Tests in PhysioCell^a.

	in vivo PK profile		in vitro dissolution test
group	Tmax [h]	C0.5 h [mg/L]	intragastric stress	GET [min]	prevalence (%)
1	≤0.5	not applicable	none	15	27
2	0.5–1.0	0.6–0.95 Cmax	300 mbar at 10 and 13 min	30	22
3	0.5–1.0	0.3–0.6 Cmax	200 mbar at 5 min	30	18
4	0.5–1.0	<0.3 Cmax	none	30	13
5	1.0–1.5	not applicable	none	60	13
6	>1.5	not applicable	none	90	7

^aC_0.5 h—drug concentration in plasma at 0.5 h; GET—complete gastric emptying time (“housekeeper wave” time).