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. 2024 Aug 26;40:30. doi: 10.1186/s42826-024-00215-5

Table 5.

Effect of β-sitosterol on oxidative stress and total antioxidants concentration of growing female rats fed a high-fructose diet

Parameter PC + PW PC + FS FF + FS Bst + PW Bst + FS Significance
TBARS (µmol/L) 14.68 ± 3.09a 24.02 ± 4.33b 17.74 ± 3.45ab 20.17 ± 3.40ab 18.61 ± 4.37ab **
T-AOC (mmol/L) 1125.53 ± 49.95a 1049.30 ± 55.25b 1133.40 ± 36.71a 1217.56 ± 54.70c 1189.03 ± 42.99ac ***

abcWithin row means with different superscripts are significantly different at p < 0.05.; ** p < 0.05; *** p < 0.0001. PC + PW = plain gelatine cubes + plain tap water to drink; PC + FS = plain gelatine cubes + 20% (w/v) fructose solution to drink; FF + FS = gelatine cube containing fenofibrate at a dose of 100 mg/kg body mass per day + fructose solution to drink. Bst + PW = gelatine cube containing β-sitosterol at a dose of 20 mg/kg body mass per day + plain tap water to drink; Bst + FS = gelatine cube containing β-sitosterol at a dose of 20 mg/kg body mass per day + fructose solution to drink (w/v); TBARS = thiobarbituric acid reactive substances; T-AOC = total antioxidant capacity. Data presented as mean ± SD; n = 7 per treatment