Table 5.
Effect of β-sitosterol on oxidative stress and total antioxidants concentration of growing female rats fed a high-fructose diet
| Parameter | PC + PW | PC + FS | FF + FS | Bst + PW | Bst + FS | Significance |
|---|---|---|---|---|---|---|
| TBARS (µmol/L) | 14.68 ± 3.09a | 24.02 ± 4.33b | 17.74 ± 3.45ab | 20.17 ± 3.40ab | 18.61 ± 4.37ab | ** |
| T-AOC (mmol/L) | 1125.53 ± 49.95a | 1049.30 ± 55.25b | 1133.40 ± 36.71a | 1217.56 ± 54.70c | 1189.03 ± 42.99ac | *** |
abcWithin row means with different superscripts are significantly different at p < 0.05.; ** p < 0.05; *** p < 0.0001. PC + PW = plain gelatine cubes + plain tap water to drink; PC + FS = plain gelatine cubes + 20% (w/v) fructose solution to drink; FF + FS = gelatine cube containing fenofibrate at a dose of 100 mg/kg body mass per day + fructose solution to drink. Bst + PW = gelatine cube containing β-sitosterol at a dose of 20 mg/kg body mass per day + plain tap water to drink; Bst + FS = gelatine cube containing β-sitosterol at a dose of 20 mg/kg body mass per day + fructose solution to drink (w/v); TBARS = thiobarbituric acid reactive substances; T-AOC = total antioxidant capacity. Data presented as mean ± SD; n = 7 per treatment