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. 2023 Sep 9;16(5):695–705. doi: 10.1177/19417381231197389

Table 1.

Primary outcomes by intervention

Intervention Body Mass Muscle Strength Sports Performance Recovery
Anabolic Steroids Evidence favors increase in lean body mass Evidence favors benefit for trained athletes; conflicting results in untrained Insufficient evidence Insufficient evidence
Growth Hormone Evidence shows increase in body weight and lean body mass and decrease in fat mass Evidence shows no benefit Potential benefit for anaerobic exercise capacity but not sports performance Insufficient evidence
Creatine Evidence supports increased body mass and lean body mass and no effect on fat mass Evidence suggests a positive effect on upper and lower body strength, at least with the short-term use Evidence shows potential benefit for short-burst anaerobic performance, but not aerobic performance. Conflicting results on change in peak power during exercise Inconclusive evidence, but possible decrease on muscle damage markers
Erythropoietin Insufficient evidence Insufficient evidence Evidence shows possible endurance benefit, V02max increase, and increase in max power output. Insufficient evidence to show that this difference translates to improvements in running, cycling, or swimming Evidence suggests no benefit
Cannabinoids Insufficient evidence Evidence suggests no benefit, and possible increased weakness Evidence shows no benefit of cannabis use on athletic or exercise performance; possible negative influence on it Insufficient evidence