Table 4.

Relationship between frailty and 30-day rehospitalizations

Frailty measure	Unadjusted		Adjusted for clinical variables1		Adjusted only for Physical Frailty Phenotype (PFP) (continuous)		Adjusted only for Short Physical Performance Battery (SPPB) (continuous)		Adjusted only for self-reported frailty (continuous)
	OR (95% CI)	p-value	OR (95% CI)	p-value	OR (95% CI)	p-value	OR (95% CI)	p-value	OR (95% CI)	p-value
PFP									.
Per 1-point increase	1.43 (1.12–1.83)	0.005	1.41 (1.09–1.83)	0.008			1.33 (1.01–1.76)	0.04	1.24 (0.95–1.62)	0.11
Frail2	3.25 (1.69–6.24)	0.0005	3.16 (1.60–6.25)	0.001			2.83 (1.37–5.81)	0.005	2.37 (1.89–4.70)	0.01
SPPB
Per 1-point increase	0.87 (0.76–0.98)	0.02	0.88 (0.77–1.01)	0.06	0.92 (0.80–1.06)	0.26			0.91 (0.80–1.04)	0.17
Frail3	2.08 (1.16–3.83)	0.01	2.12 (1.12–4.00)	0.02	1.60 (0.84–3.11)	0.15			1.66 (0.90–3.11)	0.10
Self-reported frailty
Per 10-point increase	0.52 (0.36–0.73)	0.002	0.55 (0.37–0.79)	0.001	0.57 (0.39–0.82)	0.003	0.55 (0.38–0.78)	0.0007
Frail4	2.69 (1.48–4.90)	0.001	3.00 (1.58–5.70)	0.008	2.17 (1.14–4.11)	0.02	2.39 (1.28–4.42)	0.006

¹Age, sex, white race, body mass index, pre-transplant dialysis, number of comorbidities;

²Frail = total score ≥ 3, pre-frail = total score 1–2, not frail = total score 0;

³Total score ≤ 10;

⁴Patient-Reported Outcomes Measurement Information System (PROMIS) 4-item physical function short form score < 40