Table 1.
Participant demographic characteristics.
| Total Sample: N | 108 |
|---|---|
| Age (yrs.): mean ± SD (min - max) | 55.7 ± 20.4 (22-94) |
| Sex | |
| Men: n (%) | 57 (52.8%) |
| Women: n (%) | 51 (47.2%) |
| MMSE: mean ± SD (min - max) | 28.8 ± 1.4 (25-30) |
| BMI (Kg/m2): mean ± SD (min - max) Lean (BMI < 25): n (%) Overweight (25 ≤ BMI < 30): n (%) Obese (BMI ≥ 30): n (%) |
25.8 ± 3.6 (18.2-35.8) 52 (44%) 50 (42%) 16 (14%) |
| Hypertension: n (%) | 23 (21.3%) |
|
Plasma markers Aβ42/Aβ40: mean ± SD (min - max) |
0.06 ± 0.013 (0.014-0.1) |
| pTau181 (pg/mL): mean ± SD (min - max) | 2.3 ± 1.3 (0.82-7.11) |
| NfL (pg/mL): mean ± SD (min - max) | 16.6 ± 12.7 (2.65-82.5) |
| GFAP (pg/mL): mean ± SD (min - max) | 120.5 ± 69.9 (37.9-396.1) |
SD, standard deviation; min, minimum; max, maximum; MMSE, Mini-Mental State Examination; BMI, body-mass index; Aβ, amyloid-beta; pTau, phosphorylated tau; NfL, neurofilament light chain; GFAP, glial fibrillary acidic protein.