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. 2024 Aug 25;16(1):2392875. doi: 10.1080/19490976.2024.2392875

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© 2024 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 4. — Spearman’s correlation heatmaps of pre-intervention microbiota composition and changes in markers of SkM-ox. Significant correlations in men (a) and in women (b) as results of EGCG+RES supplementation. Data on the x-axis are represented as changes in SkM-ox (week 12-week 0, δpmol O₂/mg muscle), after additions of malate+glutamate (MG, adp-stimulated state 2, complex I), malate+glutamate+succinate (MGS, state 3, complex I&II), cytochrome c (mitochondrial integrity), oligomycin (mitochondrial proton leak), and carbonyl cyanide-4-phenylhydrazone (FCCP, maximal mitochondrial respiration). A red color indicates positive correlations and blue negative. A ‘*’ indicates correlations with an fdr-adjusted P-value of Q < 0.2. Uncultured, uncultured bacterium of the Ruminococcaceae family.