Table 3. SPR kinetic parameters for Smac binding to selected BIR domains.
| Protein | kon (M−1·s−1) | koff (s−1) | Kd (nM) |
|---|---|---|---|
| MLBIR | 4.18×105 | 7.63×10−4 | 1.89 |
| MLXBIR3SG | 4.20×105 | 8.16×10−4 | 1.94 |
| XIAP-BIR2-BIR3 | 3.26×105 | 2.52×10−4 | 0.77 |
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