Figure 1. Relative composition of HDL apolipoproteins from control, apoCITg, CETPTg and CETPTg/apoCITg mice.

HDLs from control, apoCITg, CETPTg and CETPTg/apoCITg plasmas were isolated by ultracentrifugation, and their apolipoproteins were separated by SDS electrophoresis in a homogeneous polyacrylamide gel (High-Density Gel; Amersham Biosciences). Apolipoprotein bands were visualized after silver staining, and molecular masses were calculated by comparison with the relative mobility of protein standards (see the Experimental section).