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. 2004 Dec 14;385(Pt 1):189–195. doi: 10.1042/BJ20041149

Figure 5. Correlation of CETP mass concentration, total CE transfer activity and specific CETP activity with apoCI mass concentration in CETPTg/apoCITg mice.

Figure 5

Plasma CETP and apoCI mass concentrations were determined by specific immunoassays in CETPTg/apoCITg mice (n=13) (see the Experimental section). CE transfer activity was determined as the initial transfer rate of fluorescent NBD–CEs from labelled liposome donors to plasma lipoprotein acceptors, and values were normalized to plasma neutral lipid levels (see the Experimental section). Specific CETP activity in individual plasmas was obtained after correction of the total CE transfer rates by CETP mass. Variation in CETP mass and activity (y-axis) was calculated as compared with mean reference values, which were determined in parallel in CETPTg mice (n=6). Coefficients of correlation ρ were calculated by using the Spearman correlation rank analysis.