Table 1. CE and TG levels in large-sized TG-rich remnants, VLDL, LDL and HDL from control, CETPTg, apoCITg and CETPTg/apoCITg mice.
Lipid contents were determined as described in the Experimental section. Values are expressed in mmol/litre and they are the means±S.E.M. for seven (control and CETPTg mice) or five (ApoCITg and CETPTg/apoCITg) animals. The significance between mean values was determined by using ANOVA; ND, not detectable.
| Mice | ||||
|---|---|---|---|---|
| Control | CETPTg | ApoCITg | CETPTg/apoCITg | |
| TG-rich remnants | ||||
| CE | ND | ND | 0.16±0.06 | 1.09±0.42¶ |
| TG | ND | ND | 0.66±0.27 | 1.16±0.40 |
| VLDL | ||||
| CE | 0.01±0.01 | 0.03±0.01 | 0.12±0.03* | 0.47±0.08†§¶ |
| TG | 0.15±0.04 | 0.21±0.06 | 0.65±0.19†‡ | 0.86±0.14†§ |
| LDL | ||||
| CE | 0.13±0.01 | 0.20±0.02 | 0.45±0.06†§ | 0.86±0.06†§¶ |
| TG | 0.20±0.02 | 0.19±0.01 | 0.61±0.11†§ | 0.85±0.14†§ |
| HDL | ||||
| CE | 1.08±0.11 | 0.86±0.08 | 1.44±0.07*§ | 0.70±0.16*¶ |
| TG | 0.06±0.01 | 0.09±0.01 | 0.10±0.03 | 0.18±0.03†§∥ |
| Ratio of non-HDL to HDL CE | 0.14±0.03 | 0.28±0.02 | 0.56±0.09 | 5.92±2.30†§¶ |
| Ratio of HDL CE to TG | 14.5±1.4 | 11.9±2.7 | 13.2±2.6 | 4.5±1.4 |
* P<0.05, significantly different from control mice.
† P<0.005, significantly different from control mice.
‡ P<0.05, significantly different from CETPTg mice.
§ P<0.005, significantly different from CETPTg mice.
∥ P<0.05, significantly different from apoCITg mice.
¶ P<0.005, significantly different from apoCITg mice.