Table 1.
The brainlife.io processing pipeline used to process the data and extract the features of interest.
| App name | App purpose | App DOI |
|---|---|---|
| QSIPrep – preprocessing workflow | Preprocess dMRI data | brainlife.app.246 (Cieslak et al., 2021) |
| MRTrix3 – WMC Anatomically Constrained Tractography (ACT) | Build an anatomically-constrained, whole brain tractography | brainlife.app.319 (Smith et al., 2012) |
| FreeSurfer 7.1.1 | Create brain parcellations | brainlife.app.462 (Fischl, 2012) |
| Compute summary statistics of diffusion measures from Freesurfer Parcellation (volume) | Compute statistics from diffusion measures inside a parcellation generated by Freesurfer | brainlife.app.554 |
| White Matter Anatomy Segmentation | Segment the tractogram into 61 white matter tracts | brainlife.app.188 (Bullock et al., 2019) |
| Remove Tract Outliers | Remove spurious fibers from the tracts | brainlife.app.195 (Yeatman et al., 2012) |
| Generate figures of white matter tracts overlaid on anatomical image | Check white matter tract quality | brainlife.app.607 |
| Tract Analysis Profiles | Create tract profiles of microstructural white matter properties | brainlife.app.361 (Yeatman et al., 2012) |