Figure 1. Detection of LPPs by RT-PCR and Western blotting in HBEpCs.
(A) Total RNA was extracted from HBEpCs and transcription of the genes encoding LPPs (LPP-1, -2 and -3, and SPP-1) was assessed by RT-PCR (− indicates the absence of reverse transcriptase and + indicates the presence of reverse transcriptase during the RT reaction) with primers to the indicated LPPs. Lane M contains molecular size markers. (B) Cell lysates (20 μg of protein) were subjected to SDS/PAGE and analysed by Western blotting with anti-LPP-1, -LPP-2 and -LPP-3 antibodies. Each Western blot is representative of three independent experiments.