TABLE 1.

framework conditions of hemostasis by group and timepoint.

Baseline (after anesthesia)				P1	P2	P3
	Control	Fluid	catecholamine
Temperature [°C]	36.9 ± 0.9	36.5 ± 0.8	36.4 ± 0.6	0.38	0.31	0.93
Hb [g/dL]	9.3 ± 0.8	9.9 ± 0.8	10.2 ± 1.8	0.37	0.19	0.65
pH	7.489 ± 0.04	7.489 ± 0.026	7.487 ± 0.051	0.99	0.94	0.92
Lactate [mmol/L)	1.98 ± 1.55	1.42 ± 0.31	1.55 ± 0.73	0.28	0.40	0.79
Fluid volume [ml]	353 ± 137	303 ± 222	204 ± 145	0.56	0.10	0.27

T2 (60 min shock)
	Control	Fluid	catecholamine
Temperature [°C]	35.9 ± 0.7	35.9 ± 1.2	35.9 ± 0.8	0.95	0.93	0.88
Hb [g/dL]	9.2 ± 1.1	9.7 ± 0.6	9.4 ± 0.5	0.26	0.69	0.42
pH	7.395 ± 0.024	7.433 ± 0.055	7.440 ± 0.038	0.10	0.05	0.76
Lactate [mmol/L)	2.06 ± 1.17	2.42 ± 0.47	2.21 ± 0.54	0.40	0.72	0.61
Fluid volume [ml]	2057 ± 647	1786 ± 250	1757 ± 377	0.25	0.20	0.90

T4 (120 min resuscitation)
	Control	Fluid	catecholamine
Temperature [°C]	35.9 ± 1.3	34.5 ± 1	36.7 ± 1.2	0.04	0.29	<0.01
Hb [g/dL]	8.2 ± 1.7	7.1 ± 0.9	9.9 ± 1.2	0.12	0.01	<0.01
pH	7.378 ± 0.029	7.407 ± 0.057	7.296 ± 0.053	0.25	<0.01	<0.01
Lactate [mmol/L)	3.18 ± 2.27	2.05 ± 0.59	6.94 ± 1.63	0.21	<0.01	<0.01
Fluid volume [ml]	2,967 ± 703	6,774 ± 1,176	2,726 ± 523	<0.01	0.57	<0.01

Temperature measured as °C; Hb, hemoglobin measured as g/dL; lactate measured as mmol/L; Fluid volume, cumulatively infused fluids measured in ml; Control, without resuscitation; fluid, crystalloid infusion; catecholamine, norepinephrine; all parameter were stated as mean ± standard deviation; p-values: P1, control vs fluid; P2, control vs catecholamine; P3, fluid vs catecholamine; normal ranges: Hb 9–10 g/dL; Lactate under resting conditions 0.5–2.0 mmol/L; pH 7.35–7.45; temperature: 38.3°C–39.4°C.