Figure 5. Outward current in excised patches.
The bath (pH 7.0) and pipette (pHo 8.0) solutions were as described in the Materials and methods section. Excised patches were detached from CHO cells expressing EGFP-C–91 following formation of a GΩ seal. The outward currents (B) were recorded immediately after excision, in response to the voltage step protocol (A). The reversal potential of the outward current in a second excised patch was determined following an activation pulse to +100 mV (C). The first-order exponential fit of the tail currents is overlaid in grey (C). The amplitude of the tail currents (−20 mV to −80 mV) was plotted against the voltage of the repolarization step (D).