Table 2.

Concordance index of the prognostic prediction models

	Validation		Test		Combined
	C-index	p-value	C-index	p-value	C-index	p-value
CLN	0.537 (0.406, 0.668)	0.400	0.622 (0.500, 0.744)	0.020	0.585	0.002
Rad-S	0.692 (0.569, 0.815)	0.010	0.608 (0.504, 0.712)	0.050	0.645	0.013
RadCLN-S	0.697 (0.574, 0.820)	< 0.001	0.638 (0.536, 0.740)	< 0.001	0.662	0.075
Rad-D	0.748 (0.664, 0.832)	0.002	0.681 (0.573, 0.789)	0.020	0.729	0.310
RadCLN-D	0.752 (0.660, 0.844)	< 0.001	0.695 (0.581, 0.809)	0.004	0.734	–

Combined C-index is the weighted score calculated from the validation and the test set using the survcomp package in R

p-values of validation and test C-index indicate the significance of prognostic prediction (the log-rank test)

Combined p-value indicates the significance of the difference between the certain model and RadCLN-D (the student t-test)