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. Author manuscript; available in PMC: 2025 Nov 1.
Published in final edited form as: Am J Obstet Gynecol. 2024 Feb 27;231(5):552.e1–552.e13. doi: 10.1016/j.ajog.2024.02.291

Table 3.

Stem and terminal villi morphometric measures

Control N=14 HDP N=12 FGRAREDV N=14 FGRAREDV/HDP N=11
Stem Villi
Number of villi
 Mean (SD) 1174 (332) 808 (384) 982 (321) 788 (252)
Total villous area (mm2)
 Mean (SD) 18 (5) 13 (6) 16 (6) 13 (4)
Number of blood vessels
 Mean (SD) 19,017 (5684) 12,855 (6168) 16,049 (8395) 12,336 (3130)
Total blood vessel area (mm2)
 Mean (SD) 4.6 (1.7) 3.8 (2.2) 4.1 (1.5) 3.5 (1.2)
Terminal Villi
Number of villi
 Mean (SD) 3280 (832) 3363 (1065) 2211 (1053) 2728 (1520)
Total villous area (mm2)
 Mean (SD) 6 (2) 6 (2) 5 (2) 5 (3)
Number of blood vessels
 Mean (SD) 15,366 (5466) 16,272 (5266) 9603 (4942) 11,837 (6148)
Total blood vessel area (mm2)
 Mean (SD) 2.3 (0.8) 2.2 (0.8) 1.6 (0.8) 1.8 (1.1)

HDP, hypertensive disease of pregnancy; FGRAREDV, fetal growth restriction with absent or reversed umbilical artery Doppler velocimetry; FGRAREDV/HDP, combination of hypertensive disease of pregnancy and fetal growth restriction with absent or reversed umbilical artery Doppler velocimetry