TABLE 5.
The antidiarrheal and analgesic effect of different extracts of Colocasia affinis respectively on castor oil-induced and acetic acid-induced test in mice.
| Animal group with respective doses (ml/kg or mg/kg, b.w; p.o) | Number of diarrheal feces (mean ± SEM) | % Reduction of diarrhea | Number of writhing (mean ± SEM) | % Reduction of writhing |
|---|---|---|---|---|
| CTL | 8.6 ± 0.64 | - | 17.2 ± 0.38 | - |
| STD (Loperamide/Diclofenac sodium) | 2.8 ± 0.56*** | 67.44 | 3.8 ± 0.2*** | 77.91 |
| DCMSF 200 | 5.2 ± 0.16*** | 39.53 | 10.4 ± 0.51*** | 39.53 |
| DCMSF 400 | 4.2 ± 0.56* | 51.16 | 8.2 ± 0.37*** | 52.33 |
| AQSF 200 | 7 ± 0.8*** | 18.6 | 10.8 ± 0.58*** | 37.21 |
| AQSF 400 | 6.2 ± 0.56*** | 27.91 | 10.2 ± 0.8** | 40.70 |
| HSF 200 | 7.6 ± 0.24*** | 11.63 | 14 ± 0.32*** | 18.60 |
| HSF 400 | 6.8 ± 0.56*** | 20.93 | 13 ± 0.45*** | 24.42 |
| EASF 200 | 8 ± 0.8*** | 6.98 | 14.4 ± 0.51*** | 16.28 |
| EASF 400 | 7.2 ± 0.56*** | 16.28 | 12 ± 0.55*** | 30.23 |
Values are expressed as Mean ± SEM (n = 5); CTL, negative control; STD, positive control; ***p< 0.001, **p< 0.01, *p< 0.05 compared to control compared to negative control.