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. 2024 Aug 13;15:1428341. doi: 10.3389/fphar.2024.1428341

TABLE 5.

The antidiarrheal and analgesic effect of different extracts of Colocasia affinis respectively on castor oil-induced and acetic acid-induced test in mice.

Animal group with respective doses (ml/kg or mg/kg, b.w; p.o) Number of diarrheal feces (mean ± SEM) % Reduction of diarrhea Number of writhing (mean ± SEM) % Reduction of writhing
CTL 8.6 ± 0.64 - 17.2 ± 0.38 -
STD (Loperamide/Diclofenac sodium) 2.8 ± 0.56*** 67.44 3.8 ± 0.2*** 77.91
DCMSF 200 5.2 ± 0.16*** 39.53 10.4 ± 0.51*** 39.53
DCMSF 400 4.2 ± 0.56* 51.16 8.2 ± 0.37*** 52.33
AQSF 200 7 ± 0.8*** 18.6 10.8 ± 0.58*** 37.21
AQSF 400 6.2 ± 0.56*** 27.91 10.2 ± 0.8** 40.70
HSF 200 7.6 ± 0.24*** 11.63 14 ± 0.32*** 18.60
HSF 400 6.8 ± 0.56*** 20.93 13 ± 0.45*** 24.42
EASF 200 8 ± 0.8*** 6.98 14.4 ± 0.51*** 16.28
EASF 400 7.2 ± 0.56*** 16.28 12 ± 0.55*** 30.23

Values are expressed as Mean ± SEM (n = 5); CTL, negative control; STD, positive control; ***p< 0.001, **p< 0.01, *p< 0.05 compared to control compared to negative control.