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. 2005 Feb 22;386(Pt 2):315–324. doi: 10.1042/BJ20041156

Figure 4. Alignment of the amino acid sequences of QPP and DPPII, and sequence coverage of the identified tryptic peptides of the purified human DPPII.

Figure 4

(A) ClustalW multiple sequence alignment of the N-terminal sequences of human QPP (hQPP), and human and pig DPPII (hDPPII and pDPPII respectively). (B) ClustalW multiple sequence alignment of human and mouse QPP (hQPP and mQPP respectively), and rat DPPII (rDPPII). Residues most probably forming the catalytic triad are labelled with an asterisk. The consensus sequence for the active site serine residue of serine-type proteases (Gly-Xaa-Ser-Xaa-Gly) is underlined the leucine zipper motif is marked in bold. The tryptic peptide sequences of the purified human DPPII identified by MS are marked with grey boxes in the human QPP sequence. GenBank® accession numbers are as follows: hQPP, AAF12747; hDPPII, S77568; pDPPII, S70349; mQPP, AAG01154; rDPPII, Q9EPB1.