Table 1.

IC₅₀ values (µm) of polyether analogues against BLCA cells.

IC50 (µM) a)	5637	UM‐UC‐3	T24	SCaBER	RT4
End	1.24 ± 0.50	0.28 ± 0.09	0.44 ± 0.09	0.98 ± 1.19	1.07 ± 0.23
End‐5	4.30 ± 4.04	0.44 ± 0.14	2.02 ± 1.01	10.17 ± 11.79	3.72 ± 1.38
End‐2	4.02 ± 0.08	0.27 ± 0.08	0.79 ± 0.14	0.91 ± 0.69	1.27 ± 0.45
End‐3	64.74 ± 68.18	8.55 ± 6.65	18.30 ± 5.00	20.68 ± 16.03	17.58 ± 1.65
End‐4	5.06 ± 1.06	1.55 ± 0.17	1.49 ± 0.08	4.98 ± 2.98	1.89 ± 0.26
End‐16	0.89 ± 0.26	1.51 ± 0.12	0.86 ± 0.16	1.11 ± 0.56	1.27 ± 1.18
Len	0.55 ± 0.12	0.29 ± 0.03	0.43 ± 0.34	0.74 ± 0.82	0.51 ± 0.26
Len‐10	46.98 ± 41.80	12.79 ± 1.25	9.57 ± 2.33	12.78 ± 2.67	6.62 ± 2.96
Len‐11	8.49 ± 3.93	8.28 ± 6.34	3.18 ± 0.35	10.87 ± 4.91	3.51 ± 2.48
Cisplatin	2.92 ± 0.67	4.66 ± 0.74	2.48 ± 0.55	3.13 ± 0.11	3.02 ± 0.59

^a) IC₅₀ values were compared to control and were determined after exposure of the cells to different drug concentrations for 72 h. Experiments were conducted using MTT reagent. Data presented as means ± SEMs from three independent experiments.