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. 2024 Jul 29;8(3):29. doi: 10.3390/epigenomes8030029

Table 2.

Colocalization of mQTLs of CpG sites and SNPs of cardiometabolic traits in the replication study.

Trait
(Source)
CpG Site Lead SNP
(A1 Allele)
Association * Colocalization Results
B p B PSMR PHEIDI
Body fat percentage
(UKBB)
cg23627948 rs798549(C) 0.01 1.3 × 10−8 0.06 1.61 × 10−8 0.3
0.15 <2 × 10−200
DBP
(UKBB)
cg21153102 rs11070317(C) 0.18 1.7 × 10−24 2.06 6.1 × 10−23 0.3
0.09 5.2 × 10−294
Kidney function
(PMID: 31152163)
cg05280698 rs73025481(A) 0.004 2.3 × 10−23 0.04 2.5 × 10−16 0.02
0.08 3.2 × 10−47
SBP
(UKBB)
cg03186999 rs222851(A) −0.27 8.6 × 10−19 −11.22 4.3 × 10−14 0.03
0.02 1.7 × 10−47

* indicates the association of the lead SNP with the trait (first row) and the CpG site (second row).