Table 3.

Diagnostic Criteria for Postural Orthostatic Tachycardia Syndrome

Orthostatic intolerance lasting ≥6 months with the presence of the following 3 characteristics:

Increase in heart rate ≥30 bpm within 5 to 10 minutes of quiet standing or upright tilt (or ≥40 bpm in individuals 12-19 years)

Absence of orthostatic hypotension (>20 mm/Hg drop in SBP or >10 mm/Hg in DBP)

Frequent symptoms that occur on standing, such as lightheadedness, palpitations, tremulousness, generalized weakness, blurred vision, exercise intolerance, and fatigue

bpm, beats per minute; DBP, diastolic blood pressure; SBP, systolic blood pressure.

Adapted from Vernino et al.¹³