Study ID	Beta‐agonist arm			Placebo arm			Correlation
	Mean	SD	N	Mean	SD	N
Anderson 2001 Salb Disk	13.42	13.23	27	39.4	17.58	27	0.46
Anderson 2001 Salb MDI	8.51	13.75	27	39.4	17.58	27	0.46
Blake 1999 Salb 180	3.8	7.5	25	13.5	12.7	24
Blake 1999 Salm 25	7.99	10.2	26	14.0	11.5	23
Blake 1999 Salm 50	7.34	10.3	24	14.0	11.5	23
Boner 1994 Form 12	2.2	8.3	15	14.5	13.4	15
Bronski 1995 Salb MDI	16.0	11.0	44	23.0	20.0	44
Bronski 1995 Salb Pwd	26.0	13.0	44	23.0	20.0	44
Bronski 1999 Salm Disk	5.6	10.2	24	12.1	15.6	24
Bronski 1999 Salm Diskhal	5.7	6.36	24	12.1	15.6	24
Bronski 2002 Form 12	17.0	0.0	17	38.3	0.0	18
Bronski 2002 Form 24	14.6	0.0	17	38.3	0.0	18
Bronski 2002 Salb	8.6	0.0	17	37.1	0.0	18
Carlsen 1995 Salm 25	19.0	16.7	23	30.0	16.7	23
Carlsen 1995 Salm 50	18.0	14.3	23	30.0	16.7	23
Cavagni 1993 Salb Jet	7.15	4.9	8	34.7	22.3	8
Cavagni 1993 Salb MDI	15.9	9.3	9	28.9	21.8	9
Clarke 1990 Fen	‐19.9	0.0	20	9.8	0.0	20
Daugbjerg 1996 Form 12	11.0	0.0	16	35.0	0.0	16
Debelic 1988 Reproterol	12.6	0.0	16	38.5	0.0	16
DeBenedictis 1996 Salm 25	19.0	12.0	12	35.0	16.0	12	0.28
DeBenedictis 1996 Salm 50	15.0	13.0	12	35.0	16.0	12	0.33
DeBenedictis 1998 Salb	3.7	4.4	12	25.7	18.9	12
Del Col 1993 Salb Jet	20.76	2.1	15	29.14	15.1	15
Del Col 1993 Salb MDI	12.37	5.1	15	26.6	16.1	15
Dinh Xuan 1989 Terb	‐2.24	17.7	10	35.2	22.1	10
Egglestone 1981 Terb 250	10.0	8.24	17	32.0	16.49	17
Ferrari 2000 Form 12	5.9	7.2	14	29.3	14.3	14
Green 1992 Salm 50	3.2	4.8	13	26.6	10.27	13	0.30
Gronnerod 2000 Form 4.5	9.2	8.5	27	18.4	10.1	27
Gronnerod 2000 Form 9	5.4	8.5	27	18.4	10.1	27
Gronnerod 2000 Terb 500	3.3	10.2	27	18.4	10.1	27
Hawksworth 2002 Salb HFA	15.4	9	23	33.7	8.3	24
Hawksworth 2002 Salb MDI	14.9	9	24	33.7	8.3	24
Henricksen 1983 Terb	26.0	22.4	14	37.0	14.9	14
Henricksen 1992 Salb	18.0	17.3	12	44.0	13.8	12
Henriksen 1992 Form 12	8.0	10.4	12	44.0	13.8	12
Hills 1976 Salb	‐4.6	0.0	19	35.5	0.0	19
Hills 1976 Salmefamol	‐2.6	0.0	19	35.5	0.0	19
Kemp 1994 Salb	7.0	0.0	54	27.0	0.0	52
Kemp 1994 Salm 42	13.0	0.0	53	27.0	0.0	52
Konig 1981 Metaprot	19.0	12.0	24	36.0	15.0	24
Konig 1984 Fen 0.4	4.3	10.1	12	27.8	14.9	12
Konig 1984 Fen 0.8	2.5	13.0	12	27.8	14.9	12
Larsson 1982 Fen	‐2.7	0.0	8	11.0	0.0	8
McAlpine 1990 Form 12	7.7	8.6	11	32.7	16.5	11
McFadden 1986 Salb (I)	1.1	0.0	15	10.8	0.0	15
McFadden 1986 Salb (II)	‐1.1	0.0	20	14.1	0.0	20
Morton 1989 Rimet	2.8	5.5	10	24.5	8.4	10
Newnham 1993 Salb 200	3.8	18.2	11	27.1	15.9	11
Newnham 1993 Salm 50	12.8	16.9	12	32.0	23.2	11
Patel 1986 Salb 200	6.0	0.0	9	27.9	0.0	9
Patel 1986 Tulob 200	9.7	0.0	9	27.9	0.0	9
Patel 1986 Tulob 400	7.7	0.0	9	27.9	0.0	9
Patessio 1991 Form 24	10.0	0.0	12	30.5	0.0	12
Pearlman 2006 Form 12	7.6	0.0	22	13.2	0.0	20
Pearlman 2006 Form 24	5.9	0.0	23	13.2	0.0	20
Pearlman 2006 Salb 180	3.5	0.0	22	11.1	0.0	19
Pearlman 2007 Salb 90	4.8	10.8	15	22.5	10.8	15	0.39
Philip 2007 Salm 50	10.7	8.1	46	21.8	8.1	46
Richter 2002 Form 12	5.7	5.3	24	25.1	12.2	24
Richter 2002 Salm 50	7.6	7.5	24	25.1	12.2	24
Richter 2002 Terb 500	8.5	8.3	24	25.1	12.2	24
Shapiro 2002 Form 12	12.4	14.6	19	32.9	16.8	17
Shapiro 2002 Form 24	17.5	17.5	17	32.9	16.8	17
Shapiro 2002 Salb 180	10.0	18.6	19	31.1	18.7	17
Sturani 1983 Fen 400	15.8	7.9	12	36.0	6.9	12
Sturani 1983 Salb 200	23.2	8.6	12	36.0	6.9	12
VanHaitsma 2010 Salb	4.0	16.4	10	14.3	11.1	10
Vasquez 1984 Salb 400	‐0.3	4.9	13	14.3	9.8	12
Walker 1986 Bitolterol	5.0	11.4	12	23.2	16.2	12
Wolley 1990 Terb 500	17.0	6.9	12	34.0	13.8	12