Table 2.
Characteristics of the per analysis population of AB and COPD patients who previously or currently smoked (n = 152) and of its two subgroups regarding the type of chronic inflammatory airway disease (AB (n = 29) and COPD (n = 123)). The f and m regarding p values denote the level of significance with respect the differences of allele frequencies among female and male patients, respectively (bold p values represent the statistically significant (p < 0.05) results)
| Parameters | AB (n = 29 patients) | COPD (n = 123 patients) | p |
|---|---|---|---|
| Age (years) | 64 (56–70) | 69 (62–75) | 0.022 |
| Gender (f/m) | 23/6 | 51/72 | < 0.001 |
| Smoker (n/y) | 18/11 | 70/53 | 0.613 |
| Smoking (years)* | 20 (5–30) | 35 (22–45) | < 0.001 |
| Urine cotinine (ng/ml) | 46.9 (9.9–706) | 176 (9.9–2268) | 0.238 |
| Successful cessation (y/n) | 18/11 | 70/53 | 0.613 |
| Disease duration (years) | 20 (9–40) | 5 (2–14) | < 0.001 |
| Level of education (high school graduate or higher/no high school diploma) | 7/22 | 26/96 | 0.74 |
| Employment (n/y) | 22/7 | 110/12 | 0.037 |
| Family status (in relationship/single) | 15/14 | 72/50 | 0.47 |
| Number of smokers among close acquaintance (most nonsmoker/most smoker or equal number of smokers and nonsmokers) | 21/8 | 91/30 | 0.756 |
| number living in household (people) | 2 (2–4) | 2 (1–2) | 0.029 |
|
MAO-A (rs2235186) AA (f/m) AG (f/m) GG (f/m) |
4/0 10/- 9/5 |
8/22 24/- 19/50 |
0.146 |
|
COMT (rs4680) AA AG GG |
5 12 12 |
27 65 31 |
0.022 |