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. 2024 Aug 27;82:138. doi: 10.1186/s13690-024-01379-1

Table 5.

Participants’ perception about sickle cell disease and relationship choices stratified per age and sex for an exploratory study at University of Cape Coast from 2nd February to 22nd December 2022

Total Sex P-value Age (years) P-value
Female Male 15–19 20–29 30–39 ≥40
I will insist on screening for sickle cell condition before committing to a long-term relationship 0.152 0.086
 Disagree 28 (7.3) 15 (8.0) 13 (6.6) 4 (12.9) 22 (7.4) 1 (1.9) 1 (14.3)
 Uncertain 21 (5.4) 6 (3.2) 15 (7.6) 0 (0.0) 21 (7.1) 0 (0.0) 0 (0.0)
 Agree 337 (87.3) 167 (88.8) 170 (85.9) 27 (87.1) 253 (85.5) 51 (98.1) 6 (85.7)
Sickle cell condition testing is not a priority for me when it comes to marriage 0.304 0.164
 Disagree 294 (76.2) 143 (76.1) 151 (76.3) 23 (74.2) 228 (77.0) 37 (71.2) 6 (85.7)
 Uncertain 36 (9.3) 14 (7.4) 22 (11.1) 2 (6.5) 32 (10.8) 2 (3.8) 0 (0.0)
 Agree 56 (14.5) 31 (16.5) 25 (12.6) 6 (19.4) 36 (12.2) 13 (25.0) 1 (14.3)
I will not be happy if sickle cell screening is mandatory in pre-marital counseling 0.200 0.652
 Disagree 282 (73.1) 145 (77.1) 137 (69.2) 21 (67.7) 216 (73.0) 40 (76.9) 5 (71.4)
 Uncertain 36 (9.3) 14 (7.4) 22 (11.1) 2 (6.5) 28 (9.5) 6 (11.5) 0 (0.0)
 Agree 68 (17.6) 29 (15.4) 39 (19.7) 8 (25.8) 52 (17.6) 6 (11.5) 2 (28.6)
I would advise would-be couples to screen for sickle cell condition before marriage 0.420 0.551
 Disagree 27 (7.0) 15 (8.0) 12 (6.1) 2 (6.5) 22 (3.8) 2 (3.8) 1 (14.3)
 Uncertain 17 (4.4) 6 (3.2) 11 (5.6) 2 (6.5) 15 (5.1) 0 (0.0) 0 (0.0)
 Agree 342 (88.6) 167 (88.8) 175 (88.4) 27 (87.1) 259 (87.5) 50 (96.2) 6 (85.7)
Having a sickle cell condition should not deter me from marrying another person with sickle cell condition 0.143 0.190
Disagree 232 (60.1) 120 (63.8) 112 (56.6) 18 (58.1) 170 (57.4) 37 (71.2) 7 (100.0)
Uncertain 75 (19.4) 29 (15.4) 46 (23.2) 7 (22.6) 62 (20.9) 6 (11.5) 0 (0.0)
Agree 79 (20.5) 39 (20.7) 40 (20.2) 6 (19.6) 64 (21.6) 9 (17.3) 0 (0.0)
Having sickle cell disease is a matter of fate and should not be a consideration in choosing a spouse 0.081 0.433
 Disagree 263 (68.1) 132 (70.2) 131 (66.2) 21 (67.7) 203 (68.6) 33 (63.5) 6 (85.7)
 Uncertain 52 (13.5) 18 (9.6) 34 (17.2) 2 (6.5) 44 (14.9) 6 (11.5) 0 (0.0)
 Agree 71 (18.4) 38 (20.2) 33 (16.7) 8 (25.8) 49 (16.6) 13 (25.0) 1 (14.3)

The data is presented as frequencies n (%) with statistical significance at p < 0.05 determined using chi-square test