Skip to main content
. 2024 Aug 23;17:1875–1885. doi: 10.2147/CCID.S469708

Table 3.

The Effects of Chemical Peels with Carboxytherapy on Assessed Skin Parameters Related to Pigmentary and Vascular Components of the Dark Circles

Time p
Baseline After treatment
MI (carboxytherapy + ferulic acid+ ascorbic acid) – tear trough 160.9±49.4
(n=14)
142.5±46.5
(n=14)
NS (P=0.093)
MI (carboxytherapy + ferulic acid+ ascorbic acid) – the centre of the eyelid 147.5±43.1
(n=14)
131.5±43.6
(n=14)
NS (P=0.091)
EI (carboxytherapy + ferulic acid+ ascorbic acid) – tear trough 462.2±86.9
(n=14)
423.3±63.8
(n=14)
NS (P=0.069)
EI (carboxytherapy + ferulic acid+ ascorbic acid) – the centre of the eyelid 405.2±67.2
(n=14)
396.0±72.5
(n=14)
NS (P=0.593)
MI (carboxytherapy + lactobionic acid) – tear trough 101.0±38.3
(n=25)
99.1±38.1
(n=25)
NS (P=0.473)
MI (carboxytherapy + lactobionic acid) – the centre of the eyelid 98.0±29.1
(n=25)
99.9±32.2
(n=25)
NS (P=0.666)
EI (carboxytherapy + lactobionic acid) – tear trough 361.4±72.3
(n=25)
333.7±72.5
(n=25)
P=0.011
EI (carboxytherapy + lactobionic acid) – the centre of the eyelid 311.1±70.2
(n=25)
304.3±66.1
(n=25)
NS (P=0.511)

Note: Bold font indicates statistical significance.