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. 2024 Aug 27;19(8):e0306707. doi: 10.1371/journal.pone.0306707

Table 5. Effects of biofortified cow’s milk on the biochemical parameters of blood of swine female during gestation and lactation.

  Treatmentsa P-value c
Parameters CON (± SEMb) n-6 (± SEMb) n-3 (± SEMb) Treatment Time Treat*Time C1 C2
Urea, mg/dL 24.36 ± 0.06 24.89 ± 0.06 28.25 ± 0.06 0.189 0.0097 0.753 0.263 0.149
Total protein, g/dL 7.31 ± 1.75 8.12 ± 1.75 8.46 ± 1.75 0.589 <0.001 0.132 0.940 0.309
Total cholesterol, mg/dL 66.85 ± 2.82 62.86 ± 2.75 63.78 ± 2.92 0.578 <0.001 0.725 0.314 0.820
HDL, mg/dL 27.71 ± 1.77 26.54 ± 1.77 25.84 ± 1.77 0.723 <0.001 0.634 0.451 0.761
LDL, mg/dL 26.97 ± 2.79 24.15 ± 2.79 22.77 ± 2.79 0.332 <0.001 0.357 0.163 0.601
VLDL, mg/dL 6.46 ± 2.99 4.26 ± 2.99 7.84 ± 2.99 0.030 <0.001 0.061 0.500 0.011
Glucose, mg/dL 101.08 ± 2.74 97.20 ± 2.74 104.31 ± 2.74 0.313 <0.001 0.083 0.920 0.131
Triglycerides, mg/dL 88.38 ± 6.51 69.88 ± 5.10 68.03 ± 4.57 0.039 <0.001 0.040 0.012 0.788

aSows fed with a Control milk (CON), supplemented with cow’s milk biofortified with n-6 or n-3.

bSEM, standard error of the mean.

cC1, contrast Control vs n-6+n-3; C2, contrast n-6 vs n-3.