Fig 5. Anti-tumor activity of CARN87 cells in a gastric cancer immunodeficient xenograft mouse model.

(A) Schematic diagram of the CARN87 CAR construct. (B) Performance of CAR-T cells produced using lentiviral and non-viral qPB cell production. (C) Schematic diagram of in vivo NCI-N87 xenograft model experimental design. (D) Bioluminescent imaging was performed to monitor tumor cell persistence (n = 3/group). (E) Human T cell counts of blood samples taken from the indicated group of mice at day 10 and day 37 post-CAR-T injection.