Figure 2.

Similar cortical cytoarchitecture in p53-cKO mutant mice. (A) Coronal sections labeled with Nissl staining (left) and quantification of the thickness of the somatosensory area (right) (S1, orange lines). (B) Immunofluorescence for Foxp2 (left) and mean density of Foxp2+ cells in the S1 area (right) of the indicated genotypes at P60. (C) Immunofluorescence for Cux1 (left) and mean density of Cux1+ cells in the S1 area (right) of the indicated genotypes at P60 (D) Coronal sections at the level of the S1 area hybridized with Gad67 riboprobe in control and p53-cKO mice (left) and mean density of Gad67+ cells in the S1 area (right) of the indicated genotypes at P60. Values were obtained by unpaired Student’s t-test for (C) and (D) and Mann -Whitney test for Foxp2 quantification (B); *p < 0.05, **p < 0.01, and ***p < 0.001. Scale bar (A) 1 mm, (B–D) 100 μm.