Table 1.
Patient demographics of the study cohort.
| hCG LPS group (n=1910) |
Non-hCG LPS group (n=2852) |
P value | |
|---|---|---|---|
| Female age at OPU (y) | 30.75 ± 3.83 | 30.62 ± 3.71 | 0.241 |
| Female age at FET (y) | 31.73 ± 3.68 | 31.63 ± 3.59 | 0.340 |
| Male age (y) | 33.17 ± 4.28 | 33.13 ± 4.31 | 0.748 |
| BMI, kg/m2 | 21.85 ± 2.73 | 21.76 ± 2.89 | 0.322 |
| Years of infertility | 3.39 ± 2.41 | 3.37 ± 2.44 | 0.731 |
| Parity | 0.776 | ||
| Primipara, n (%) | 82.04 (1567/1910) | 82.36 (2349/2852) | |
| Multipara (%) | 17.96 (343/1910) | 17.64 (503 /2852) | |
| Type of infertility | 0.251 | ||
| Primary infertility, n (%) | 52.51 (1003 /1910) | 54.21 (1546 /2852) | |
| Secondary infertility, n (%) | 47.49 (907 /1910) | 45.79 (1306 /2852) | |
| Cause of infertility | 0.960 | ||
| Tubal factor, n (%) | 39.01 (745/1910) | 39.13 (1116 /2852) | |
| Ovulation factor, n (%) | 4.66 (89/1910) | 2.91 (83 /2852) | |
| Male factor, n (%) | 15.55 (297 /1910) | 18.34 (523 /2852) | |
| Combined factors, n (%) | 36.39 (695/1910) | 35.06 (1000 /2852) | |
| Unknown factor, n (%) | 4.40 (84/1910) | 4.56(130/2852) | |
| Basal FSH | 7.22 ± 2.90 | 7.16 ± 2.72 | 0.509 |
| Basal LH | 5.44 ± 15.39 | 5.22 ± 6.12 | 0.498 |
| No. of oocytes retrieved (n) | 12.08 ± 5.68 | 12.76 ± 5.96 | <0.001 |
| Insemination type | 0.151 | ||
| IVF, n (%) | 78.85(1506/1910) | 77.14 (2200/2852) | |
| ICSI, n (%) | 21.15(404/1910) | 22.86 (652/2852) | |
| Freeze all, n (%) | 45.50(869/1910) | 45.65(1302/2852) | 0.916 |
| Endometrial thickness (mm) | 11.30 ± 1.84 | 11.16 ± 2.61 | 0.038 |
| hCG trigger, n (%) | 62.83 (1200/1910) | 30.40 (867/2852) | <0.001 |
| Total No. of blastocysts transferred (n) | 2344 | 3595 | |
| Mean No. of blastocysts transferred (n) | 1.23 ± 0.42 | 1.26 ± 0.44 | 0.009 |
| Good quality blastocyst transfer | <0.001 | ||
| None, n (%) | 52.04 (994/1910) | 44.60 (1272/2852) | |
| ≥1, n (%) | 47.96 (916/1910) | 55.40 (1580/2852) | |
| Type of blastocyst transfer | 0.432 | ||
| Day 5 blastocyst, n (%) | 88.44 (2073/2344) | 87.76 (3155/3595) | |
| Day 6 blastocyst, n (%) | 11.56 (271 /2344) | 12.24 (440/3595) |
OPU, Oocyte pick up; FET, Frozen-thawed embryo transfer; FSH, Follicle stimulating hormone; LH, Luteinizing hormone. Data are presented as mean ± SD or n (%); Statistical significance is defined as P<0.05.